Berberine
Also known as: Berberine HCL, Berberine Hydrochloride
Berberine is a bioactive compound found in several plants. It has potent effects on blood sugar metabolism, comparable to some pharmaceutical drugs. It's one of the few supplements with drug-like effects.
Potential Benefits
- May significantly lower blood sugar
- May improve insulin sensitivity
- May lower cholesterol and triglycerides
- May support weight loss
- Antimicrobial properties
What Research Shows
Strong evidence for blood sugar reduction, comparable to metformin in some studies. Good evidence for lipid improvements. Effects are significant enough to require caution.
Dosage Information
500mg 2-3 times daily with meals (total 1000-1500mg daily)
Note: Optimal dosing may vary based on individual factors. Always follow product label instructions or consult a healthcare provider.
Side Effects
- GI issues: diarrhea, constipation, flatulence, stomach pain
- May cause low blood sugar when combined with diabetes meds
- Possible cramping
Drug Interactions
- Diabetes medications (may cause hypoglycemia)
- Medications metabolized by CYP enzymes
- Blood pressure medications
- Antibiotics
Natural Sources
Products Containing Berberine
Medical Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before taking any supplement, especially if you have medical conditions or take medications.